Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NTN1Netrin 1. (558 aa)    
Predicted Functional Partners:
UNC5A
Unc-5 netrin receptor A.
    
 0.965
DCC
DCC netrin 1 receptor.
    
 0.962
UNC5B
Unc-5 netrin receptor B.
   
 0.961
UNC5C
Unc-5 netrin receptor C.
    
 0.950
UNC5D
Unc-5 netrin receptor D.
    
 0.934
NEO1
Neogenin 1.
    
 0.851
IGDCC4
Immunoglobulin superfamily DCC subclass member 4.
    
 0.711
DSCAM
DS cell adhesion molecule.
   
 0.706
DSCAML1
DS cell adhesion molecule like 1.
   
 0.706
DRAXIN
Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
    
 
 0.648
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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