Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ASCL4Achaete-scute family bHLH transcription factor 4. (173 aa)    
Predicted Functional Partners:
TCF12
Transcription factor 12.
   
 0.707
TCF4
Transcription factor 4.
   
 0.707
TCF3
Transcription factor 3.
   
 0.680
BHLHA9
Basic helix-loop-helix family member a9.
      
 0.672
MAIP1
Matrix AAA peptidase interacting protein 1.
      
 0.628
ID2
Inhibitor of DNA binding 2.
    
 0.584
ID4
Inhibitor of DNA binding 4, HLH protein.
    
 0.584
OLIG3
Oligodendrocyte transcription factor 3.
   
 
 0.581
ACSL4
Acyl-CoA synthetase long chain family member 4.
    
 
 0.548
TMEM63C
Transmembrane protein 63C.
      
 0.545
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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