Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CGRRF1Cell growth regulator with ring finger domain 1. (332 aa)    
Predicted Functional Partners:
CGREF1
Cell growth regulator with EF-hand domain 1.
      
 0.780
ANKLE2
Ankyrin repeat and LEM domain containing 2.
    
 
 0.625
RNF145
Ring finger protein 145.
    
 
 0.620
RNF130
Ring finger protein 130.
     
 0.609
FAM8A1
Family with sequence similarity 8 member A1.
      
 0.601
RNF170
Ring finger protein 170.
      
 0.575
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
      
 0.574
RNF19B
RBR-type E3 ubiquitin transferase.
   
 0.531
CNIH1
Cornichon family AMPA receptor auxiliary protein 1.
      
 0.517
LSG1
Large 60S subunit nuclear export GTPase 1.
      
 0.499
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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