STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPC25SPC25 component of NDC80 kinetochore complex. (226 aa)    
Predicted Functional Partners:
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.999
NDC80
NDC80 kinetochore complex component.
   
 0.999
SPC24
Uncharacterized protein.
   
 0.998
DSN1
DSN1 component of MIS12 kinetochore complex.
   
 0.991
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.990
NSL1
NSL1 component of MIS12 kinetochore complex.
   
 0.990
MIS12
MIS12 kinetochore complex component.
    
 0.989
BUB1B
Uncharacterized protein.
   
 0.986
ZWINT
ZW10 interacting kinetochore protein.
   
 0.986
PMF1
Uncharacterized protein.
   
  0.955
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.