Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SEPHS1Selenophosphate synthetase 1. (392 aa)    
Predicted Functional Partners:
SCLY
Selenocysteine lyase.
   
 0.926
TXNRD2
Thioredoxin reductase 2.
  
 
 0.893
SEPSECS
O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis.
     
 0.888
SEPHS2
Selenophosphate synthetase 2.
     
  0.851
TXNRD3
Thioredoxin reductase 3.
  
 
 0.820
TXNRD1
Thioredoxin reductase 1.
  
 
 0.820
MOCOS
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
    
 0.603
EEFSEC
Eukaryotic elongation factor, selenocysteine-tRNA specific.
     
 0.591
G3U337_LOXAF
40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family.
 
    
 0.553
SELENOS
Selenoprotein S.
   
  
 0.496
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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