Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
USP31Uncharacterized protein. (283 aa)    
Predicted Functional Partners:
USP43
Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family.
 
     0.922
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.642
PTPRQ
Protein tyrosine phosphatase receptor type Q.
    
 
 0.581
CDH23
Cadherin related 23.
      
 0.577
RFC4
Replication factor C subunit 4.
   
 0.559
USP10
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
    
 0.557
EDNRB
Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.
    
 0.556
UBB
Ubiquitin B.
    
 0.556
UBC
Uncharacterized protein.
    
 0.556
POLH
DNA polymerase eta.
   
 
 0.549
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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