Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KRT35Keratin 35; Belongs to the intermediate filament family. (455 aa)    
Predicted Functional Partners:
KRT32
Keratin 32; Belongs to the intermediate filament family.
   
 
  0.947
KRT36
Keratin 36; Belongs to the intermediate filament family.
   
 
 0.935
KRT24
Keratin 24; Belongs to the intermediate filament family.
   
 
  0.843
KRTAP3-1
Keratin associated protein 3-1.
   
 
 0.755
KRT27
Keratin 27; Belongs to the intermediate filament family.
   
 0.752
KRTAP11-1
Keratin associated protein 11-1.
   
  
 0.718
PKP1
Plakophilin 1.
   
 0.675
PTPRM
Protein tyrosine phosphatase receptor type M.
   
 0.599
KRT82
Keratin 82; Belongs to the intermediate filament family.
   
0.599
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 
 0.587
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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