STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (359 aa)    
Predicted Functional Partners:
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
     
0.974
VEGFB
Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family.
    
0.958
FLT1
Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.945
PDGFC
Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family.
     
 0.943
PGF
Placental growth factor; Belongs to the PDGF/VEGF growth factor family.
     
0.941
VEGFA
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
0.935
PDGFD
Platelet derived growth factor D.
     
 0.923
KDR
Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.917
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
     
 0.913
HGF
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 
 0.913
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.