STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PIRPirin; Belongs to the pirin family. (290 aa)    
Predicted Functional Partners:
PDGFD
Platelet derived growth factor D.
     
 0.759
PDGFA
Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family.
   
 0.753
PDGFB
Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.
     
 0.741
LOC100658583
Uncharacterized protein.
     
 0.686
PDGFC
Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family.
     
 0.685
INSRR
Insulin receptor related receptor.
    
 0.677
NGFR
Nerve growth factor receptor.
     
 0.670
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.669
C2orf68
Chromosome 2 open reading frame 68.
    
   0.657
INSR
Tyrosine-protein kinase receptor.
    
 0.657
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.