STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIRPirin; Belongs to the pirin family. (290 aa)    
Predicted Functional Partners:
PIWIL4
Piwi like RNA-mediated gene silencing 4; Belongs to the argonaute family.
      
 0.686
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
 
   
 0.638
PIWIL2
Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.
      
 0.585
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.553
CTF1
Cardiotrophin 1.
      
 0.543
CEACAM16
Carcinoembryonic antigen related cell adhesion molecule 16.
   
 0.522
BCL3
BCL3 transcription coactivator.
   
 0.522
ATG101
Autophagy related 101.
      
 0.521
INSRR
Insulin receptor related receptor.
    
 0.494
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
   
 
 0.474
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.