STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PROP1PROP paired-like homeobox 1. (188 aa)    
Predicted Functional Partners:
CRH
Corticotropin releasing hormone.
      
 0.757
STAT3
Signal transducer and activator of transcription.
      
 0.723
POU1F1
POU domain protein.
    
 
 0.676
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
    
 
 0.624
GHRHR
Growth hormone releasing hormone receptor.
   
  
 0.568
PRL
Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.
   
  
 0.526
LHX3
LIM homeobox 3.
   
0.501
LHX4
LIM homeobox 4.
   
0.445
GHRH
Growth hormone releasing hormone.
      
 0.439
CBS
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
      
 0.435
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.