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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAMD1Sterile alpha motif domain containing 1. (292 aa)    
Predicted Functional Partners:
MEAF6
MYST/Esa1 associated factor 6.
    
 0.768
RUVBL1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
   
 0.739
DMAP1
DNA methyltransferase 1 associated protein 1.
   
 0.702
TRRAP
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.702
G3U6X7_LOXAF
Uncharacterized protein.
   
 0.702
WRN
WRN RecQ like helicase.
    
 0.666
MRGBP
MRG domain binding protein.
    
 0.634
BRD1
Bromodomain containing 1.
    
 0.615
BRPF1
Bromodomain and PHD finger containing 1.
    
 0.615
BRPF3
Bromodomain and PHD finger containing 3.
    
 0.615
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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