STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MVB12BMultivesicular body subunit 12B. (317 aa)    
Predicted Functional Partners:
TSG101
Tumor susceptibility 101.
    
 0.988
VPS37B
VPS37B subunit of ESCRT-I.
   
 0.988
VPS28
Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.
   
 0.987
VPS37A
VPS37A subunit of ESCRT-I.
   
 0.959
UEVLD
UEV and lactate/malate dehyrogenase domains.
    
 0.911
VPS37C
VPS37C subunit of ESCRT-I.
   
 0.908
VPS36
Vacuolar protein sorting 36 homolog.
     
 0.889
SNF8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
     
 0.877
VPS25
Vacuolar protein sorting 25 homolog.
    
 0.875
VPS37D
VPS37D subunit of ESCRT-I.
   
 0.869
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.