Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ERG28Ergosterol biosynthesis 28 homolog. (140 aa)    
Predicted Functional Partners:
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 
 0.949
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 
 0.881
SIGMAR1
Sigma non-opioid intracellular receptor 1.
   
 
 0.879
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
    
 
 0.872
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
   
 
 0.869
HSD17B7-2
Uncharacterized protein.
   
 
 0.799
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 
 0.799
NSDHL
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
   
 
 0.721
TM7SF2
Transmembrane 7 superfamily member 2.
   
 
 0.712
DHCR7
7-dehydrocholesterol reductase.
   
 
 0.712
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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