Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC78Coiled-coil domain containing 78. (421 aa)    
Predicted Functional Partners:
BBOF1
Basal body orientation factor 1.
   
 
 0.670
DEUP1
Deuterosome assembly protein 1.
    
 
 0.619
MCIDAS
Multiciliate differentiation and DNA synthesis associated cell cycle protein.
      
 0.592
CKAP5
Cytoskeleton associated protein 5.
   
 0.562
TTC21B
Tetratricopeptide repeat domain 21B.
   
 
 0.546
SPEG
Striated muscle enriched protein kinase.
    
 0.545
PRC1
Protein regulator of cytokinesis 1.
   
 
 0.522
RSPH3
Radial spoke head 3.
   
  
 0.510
PCSK6
Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family.
      
 0.505
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.498
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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