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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCUMitochondrial calcium uniporter. (354 aa)    
Predicted Functional Partners:
MICU1
Mitochondrial calcium uptake 1.
    
 0.991
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
    
 0.989
MICU2
Mitochondrial calcium uptake 2.
    
 0.977
MCUB
Mitochondrial calcium uniporter dominant negative beta subunit.
  
 
0.833
MICU3
Mitochondrial calcium uptake family member 3.
     
 0.753
TIMM8A
Translocase of inner mitochondrial membrane 8A; Belongs to the small Tim family.
      
 0.659
COX11
Cytochrome c oxidase copper chaperone COX11.
      
 0.639
NDUFS4
Uncharacterized protein.
      
 0.624
PHB2
Prohibitin.
     
 0.605
MCUR1
Mitochondrial calcium uniporter regulator 1.
    
 
 0.592
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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