EFCAB7 protein (Loxodonta africana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

EFCAB7

EF-hand calcium binding domain 7. (629 aa)

Predicted Functional Partners:

IQCE

0.979

EVC2

0.946

EVC

0.932

SPA17

0.927

AKAP14

0.810

TTC23L

0.793

TTC23

0.788

RFFL

0.775

DLG5

0.705

ST13

0.678

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP14	EFCAB7	ENSLAFP00000002467	ENSLAFP00000004030	Uncharacterized protein.	EF-hand calcium binding domain 7.	0.810
AKAP14	SPA17	ENSLAFP00000002467	ENSLAFP00000013651	Uncharacterized protein.	Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.	0.963
DLG5	EFCAB7	ENSLAFP00000003418	ENSLAFP00000004030	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.	EF-hand calcium binding domain 7.	0.705
DLG5	EVC	ENSLAFP00000003418	ENSLAFP00000008635	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.	EvC ciliary complex subunit 1.	0.417
DLG5	EVC2	ENSLAFP00000003418	ENSLAFP00000005869	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.	EvC ciliary complex subunit 2.	0.737
DLG5	IQCE	ENSLAFP00000003418	ENSLAFP00000009674	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.	IQ motif containing E.	0.588
EFCAB7	AKAP14	ENSLAFP00000004030	ENSLAFP00000002467	EF-hand calcium binding domain 7.	Uncharacterized protein.	0.810
EFCAB7	DLG5	ENSLAFP00000004030	ENSLAFP00000003418	EF-hand calcium binding domain 7.	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.	0.705
EFCAB7	EVC	ENSLAFP00000004030	ENSLAFP00000008635	EF-hand calcium binding domain 7.	EvC ciliary complex subunit 1.	0.932
EFCAB7	EVC2	ENSLAFP00000004030	ENSLAFP00000005869	EF-hand calcium binding domain 7.	EvC ciliary complex subunit 2.	0.946
EFCAB7	IQCE	ENSLAFP00000004030	ENSLAFP00000009674	EF-hand calcium binding domain 7.	IQ motif containing E.	0.979
EFCAB7	RFFL	ENSLAFP00000004030	ENSLAFP00000015352	EF-hand calcium binding domain 7.	RING-type domain-containing protein.	0.775
EFCAB7	SPA17	ENSLAFP00000004030	ENSLAFP00000013651	EF-hand calcium binding domain 7.	Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.	0.927
EFCAB7	ST13	ENSLAFP00000004030	ENSLAFP00000006139	EF-hand calcium binding domain 7.	ST13 Hsp70 interacting protein.	0.678
EFCAB7	TTC23	ENSLAFP00000004030	ENSLAFP00000025899	EF-hand calcium binding domain 7.	Tetratricopeptide repeat domain 23.	0.788
EFCAB7	TTC23L	ENSLAFP00000004030	ENSLAFP00000006092	EF-hand calcium binding domain 7.	Tetratricopeptide repeat domain 23 like.	0.793
EVC	DLG5	ENSLAFP00000008635	ENSLAFP00000003418	EvC ciliary complex subunit 1.	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.	0.417
EVC	EFCAB7	ENSLAFP00000008635	ENSLAFP00000004030	EvC ciliary complex subunit 1.	EF-hand calcium binding domain 7.	0.932
EVC	EVC2	ENSLAFP00000008635	ENSLAFP00000005869	EvC ciliary complex subunit 1.	EvC ciliary complex subunit 2.	0.994
EVC	IQCE	ENSLAFP00000008635	ENSLAFP00000009674	EvC ciliary complex subunit 1.	IQ motif containing E.	0.930

page 1 of 2

Server load: low (16%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About