STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)    
Predicted Functional Partners:
G3U937_LOXAF
Dilute domain-containing protein.
 
  
 
 0.820
WIPF2
WAS/WASL interacting protein family member 2.
   
 
 0.777
WAS
WASP actin nucleation promoting factor.
   
 
 0.728
WASL
WASP like actin nucleation promoting factor.
   
 
 0.700
OSTF1
Osteoclast stimulating factor 1.
    
 0.698
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.657
DAB2
DAB adaptor protein 2.
   
  
 0.604
PSTPIP1
Proline-serine-threonine phosphatase interacting protein 1.
   
 
 0.592
MYO3B
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
 
 
 
 0.592
ARPC3
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
    
 
 0.587
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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