STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)    
Predicted Functional Partners:
G3U937_LOXAF
Dilute domain-containing protein.
 
  
 
 0.799
WAS
WASP actin nucleation promoting factor.
   
 
 0.775
WIPF2
WAS/WASL interacting protein family member 2.
    
 
 0.770
WASL
WASP like actin nucleation promoting factor.
   
 
 0.739
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.605
CLTC
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
      
 0.570
MYO3B
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
 
 
  
 0.555
UNC45A
Unc-45 myosin chaperone A.
    
 
 0.534
UNC45B
Unc-45 myosin chaperone B.
    
 
 0.534
TRIP10
Thyroid hormone receptor interactor 10.
   
 
 0.527
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.