STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTA3Metastasis associated 1 family member 3. (532 aa)    
Predicted Functional Partners:
GATAD2B
GATA zinc finger domain containing 2B.
   
 0.899
CHD4
Uncharacterized protein.
   
 0.893
CHD3
Chromodomain helicase DNA binding protein 3.
   
 0.880
GATAD2A
GATA zinc finger domain containing 2A.
   
 0.874
MTA1
Metastasis associated 1.
  
 
0.812
RBBP4
RB binding protein 4, chromatin remodeling factor.
   
 0.797
RBBP7
RB binding protein 7, chromatin remodeling factor.
   
 0.797
MBD2
Methyl-CpG binding domain protein 2.
   
 0.768
MBD3
Methyl-CpG binding domain protein 3.
   
 0.768
KDM1A
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.738
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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