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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSD17B13Hydroxysteroid 17-beta dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (253 aa)    
Predicted Functional Partners:
CD3E
CD3e molecule.
   
 0.728
CD247
CD247 molecule.
   
 0.605
CD3G
CD3g molecule.
   
 0.603
FDX1
Uncharacterized protein.
   
 0.499
HIRA
Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.
    
 0.469
DHRS9
Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.466
RLBP1
Retinaldehyde binding protein 1.
    
 0.458
RDH16
Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.454
RDH5
Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.453
SDR9C7
Short chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.453
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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