Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
BHLHE40Basic helix-loop-helix family member e40. (412 aa)    
Predicted Functional Partners:
ARNTL
Aryl hydrocarbon receptor nuclear translocator like.
    
 0.973
G3UCX2_LOXAF
BHLH domain-containing protein.
   
 0.928
ARNTL2
Aryl hydrocarbon receptor nuclear translocator like 2.
    
 0.893
CLOCK
Clock circadian regulator.
    
 0.893
NPAS2
Neuronal PAS domain protein 2.
    
 0.893
CRY1
Cryptochrome circadian regulator 1.
    
 
 0.737
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 
 0.707
NR1D1
Nuclear receptor subfamily 1 group D member 1.
      
 0.705
NR1D2
Nuclear receptor subfamily 1 group D member 2.
    
 
 0.703
PSMB2
Proteasome subunit beta.
    
 
 0.629
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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