STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ALKBH4AlkB homolog 4, lysine demethylase. (298 aa)    
Predicted Functional Partners:
ALKBH1
AlkB homolog 1, histone H2A dioxygenase.
   
  
 0.811
ATR
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
   0.803
RAPGEF1
Rap guanine nucleotide exchange factor 1.
     
  0.704
METTL4
Methyltransferase like 4; Belongs to the MT-A70-like family.
      
 0.700
N6AMT1
N-6 adenine-specific DNA methyltransferase 1.
      
 0.681
ALKBH6
Uncharacterized protein.
      
 0.669
APEX1
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
 
      0.645
ALKBH7
AlkB homolog 7.
   
  
 0.643
ALKBH2
AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase.
      
 0.600
KLHL31
Kelch like family member 31.
      
 0.563
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.