STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)    
Predicted Functional Partners:
PARD6A
Par-6 family cell polarity regulator alpha.
    
 0.972
PARD3
Par-3 family cell polarity regulator.
    
 0.972
LLGL1
LLGL scribble cell polarity complex component 1.
    
 0.950
LLGL2
LLGL scribble cell polarity complex component 2.
    
 0.950
PARD6G
Par-6 family cell polarity regulator gamma.
    
 0.911
PARD6B
Par-6 family cell polarity regulator beta.
    
 0.911
CDC42
Uncharacterized protein.
    
 0.899
SQSTM1
Sequestosome 1.
    
 0.881
PIAS4
Protein inhibitor of activated STAT 4.
    
 0.863
TIAM1
T cell lymphoma invasion and metastasis 1.
    
 0.858
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.