STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAP2ArfGAP with dual PH domains 2. (383 aa)    
Predicted Functional Partners:
ARFGAP1
ADP ribosylation factor GTPase activating protein 1.
    
 0.611
RPS6KC1
Ribosomal protein S6 kinase C1.
      
 0.490
RPS6KL1
Ribosomal protein S6 kinase like 1.
      
 0.469
UTP6
UTP6 small subunit processome component.
      
 0.468
COPRS
Coordinator of PRMT5 and differentiation stimulator.
      
 0.463
NCL
Nucleolin.
    
 
 0.462
RNF135
Ring finger protein 135.
      
 0.459
TEFM
Transcription elongation factor, mitochondrial.
      
 0.451
AGFG2
ArfGAP with FG repeats 2.
   
 
 0.450
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 0.433
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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