Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RPRD2Regulation of nuclear pre-mRNA domain containing 2. (1481 aa)    
Predicted Functional Partners:
RPRD1B
Regulation of nuclear pre-mRNA domain containing 1B.
    
0.986
RPAP2
RNA polymerase II associated protein 2.
   
 0.983
RPRD1A
Regulation of nuclear pre-mRNA domain containing 1A.
    
0.975
POLR2G
RNA polymerase II subunit G.
    
  0.971
POLR2M
RNA polymerase II subunit M.
    
 0.873
SUPT5H
Transcription elongation factor SPT5.
   
 0.872
POLR2E
RNA polymerase II subunit E.
    
  0.848
POLR2C
RNA polymerase II subunit C.
    
 0.842
POLR2I
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
    
 0.821
POLR2F
RNA polymerase II subunit F.
    
  0.815
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: medium (68%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.