STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GIT1GIT ArfGAP 1. (770 aa)    
Predicted Functional Partners:
GIT2
GIT ArfGAP 2.
   
  0.983
ARHGEF7
Rho guanine nucleotide exchange factor 7.
   
 0.967
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
   
 0.967
LPXN
Leupaxin.
    
 0.955
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.955
CDC42
Uncharacterized protein.
    
 0.939
PAK2
Non-specific serine/threonine protein kinase.
    
 0.910
PAK3
Non-specific serine/threonine protein kinase.
    
 0.902
PAK1
Non-specific serine/threonine protein kinase.
    
 0.902
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.854
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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