STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GIT1GIT ArfGAP 1. (770 aa)    
Predicted Functional Partners:
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.979
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.977
ITSN2
Intersectin 2.
   
 
 0.953
G3U095_LOXAF
Uncharacterized protein.
   
 
 0.953
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.806
LPXN
Leupaxin.
    
 
 0.785
PAK2
Non-specific serine/threonine protein kinase.
    
 0.719
GIT2
GIT ArfGAP 2.
  
 
0.703
CDC42
Uncharacterized protein.
    
 0.687
NCK2
Cytoplasmic protein.
    
 0.666
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.