STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CORO6Coronin; Belongs to the WD repeat coronin family. (472 aa)    
Predicted Functional Partners:
CORO1C
Coronin; Belongs to the WD repeat coronin family.
   
   0.932
CORO1B
Coronin; Belongs to the WD repeat coronin family.
    
   0.809
ARHGEF5
Uncharacterized protein.
      
 0.729
CORO1A
Coronin; Belongs to the WD repeat coronin family.
   
   0.717
SCIN
Scinderin.
   
 
 0.699
GSN
Gelsolin.
   
 
 0.687
CFL1
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 0.656
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 0.624
C5orf30
Chromosome 5 open reading frame 30.
      
 0.550
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.549
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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