TMPRSS4 protein (Loxodonta africana) - STRING interaction network

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TMPRSS4

Transmembrane serine protease 4; Belongs to the peptidase S1 family. (433 aa)

Predicted Functional Partners:

TMPRSS2

0.946

MST1R

0.507

MET

0.507

FURIN

0.443

TMPRSS11F

0.404

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FURIN	TMPRSS11F	ENSLAFP00000002835	ENSLAFP00000014930	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Transmembrane protease serine; Belongs to the peptidase S1 family.	0.430
FURIN	TMPRSS2	ENSLAFP00000002835	ENSLAFP00000025718	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	0.713
FURIN	TMPRSS4	ENSLAFP00000002835	ENSLAFP00000004175	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.443
MET	MST1R	ENSLAFP00000009780	ENSLAFP00000005642	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Macrophage stimulating 1 receptor.	0.700
MET	TMPRSS11F	ENSLAFP00000009780	ENSLAFP00000014930	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Transmembrane protease serine; Belongs to the peptidase S1 family.	0.507
MET	TMPRSS2	ENSLAFP00000009780	ENSLAFP00000025718	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	0.512
MET	TMPRSS4	ENSLAFP00000009780	ENSLAFP00000004175	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.507
MST1R	MET	ENSLAFP00000005642	ENSLAFP00000009780	Macrophage stimulating 1 receptor.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.700
MST1R	TMPRSS11F	ENSLAFP00000005642	ENSLAFP00000014930	Macrophage stimulating 1 receptor.	Transmembrane protease serine; Belongs to the peptidase S1 family.	0.507
MST1R	TMPRSS2	ENSLAFP00000005642	ENSLAFP00000025718	Macrophage stimulating 1 receptor.	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	0.507
MST1R	TMPRSS4	ENSLAFP00000005642	ENSLAFP00000004175	Macrophage stimulating 1 receptor.	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.507
TMPRSS11F	FURIN	ENSLAFP00000014930	ENSLAFP00000002835	Transmembrane protease serine; Belongs to the peptidase S1 family.	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	0.430
TMPRSS11F	MET	ENSLAFP00000014930	ENSLAFP00000009780	Transmembrane protease serine; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.507
TMPRSS11F	MST1R	ENSLAFP00000014930	ENSLAFP00000005642	Transmembrane protease serine; Belongs to the peptidase S1 family.	Macrophage stimulating 1 receptor.	0.507
TMPRSS11F	TMPRSS4	ENSLAFP00000014930	ENSLAFP00000004175	Transmembrane protease serine; Belongs to the peptidase S1 family.	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.404
TMPRSS2	FURIN	ENSLAFP00000025718	ENSLAFP00000002835	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	0.713
TMPRSS2	MET	ENSLAFP00000025718	ENSLAFP00000009780	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.512
TMPRSS2	MST1R	ENSLAFP00000025718	ENSLAFP00000005642	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	Macrophage stimulating 1 receptor.	0.507
TMPRSS2	TMPRSS4	ENSLAFP00000025718	ENSLAFP00000004175	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	0.946
TMPRSS4	FURIN	ENSLAFP00000004175	ENSLAFP00000002835	Transmembrane serine protease 4; Belongs to the peptidase S1 family.	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	0.443

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