STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KRT80Keratin 80; Belongs to the intermediate filament family. (450 aa)    
Predicted Functional Partners:
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
    
 0.909
DSG1
Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
     
 0.878
DSG2
Desmoglein 2.
     
 0.876
KRT32
Keratin 32; Belongs to the intermediate filament family.
    
 0.760
KRT19
Keratin 19; Belongs to the intermediate filament family.
   
  0.750
C9orf116
Chromosome 9 open reading frame 116.
      
 0.711
KRT23
Keratin 23; Belongs to the intermediate filament family.
     
 0.595
G3UGM0_LOXAF
Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family.
      
 0.561
HPS5
Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
      
 0.559
VSTM2L
V-set and transmembrane domain containing 2 like.
      
 0.511
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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