Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (808 aa)    
Predicted Functional Partners:
PLXNB2
Sema domain-containing protein.
    
 0.902
SEMA4D
Sema domain-containing protein; Belongs to the semaphorin family.
    
 0.845
G3SX85_LOXAF
Sema domain-containing protein; Belongs to the semaphorin family.
    
 0.842
PLXNB3
Plexin B3.
    
 0.839
PLXNB1
Plexin B1.
    
 0.839
SEMA4C
Semaphorin 4C; Belongs to the semaphorin family.
    
 0.826
SEMA4A
Semaphorin 4A; Belongs to the semaphorin family.
     
 0.762
SEMA4F
Ssemaphorin 4F; Belongs to the semaphorin family.
    
 0.645
PPAT
Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
      
 0.578
GOT1
Aspartate aminotransferase.
      
 0.571
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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