STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PON1Paraoxonase 1. (356 aa)    
Predicted Functional Partners:
APOA4
Apolipoprotein A4.
   
 
 0.818
CLU
Clusterin; Belongs to the clusterin family.
    
 0.812
CETP
Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
     
 0.755
APOE
Apolipoprotein E.
   
 
 0.728
APOA2
Apolipoprotein A2.
   
 
 0.728
LCAT
Lecithin-cholesterol acyltransferase.
   
 
 0.694
APOB
Apolipoprotein B.
   
 
 0.686
APOC1
Apolipoprotein C1.
   
 
 0.626
APOC3
Apolipoprotein C3.
   
 
 0.598
PLTP
Phospholipid transfer protein.
     
 0.578
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.