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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNJ1Potassium voltage-gated channel subfamily J member 1. (391 aa)    
Predicted Functional Partners:
SGK1
Non-specific serine/threonine protein kinase.
     
 0.934
SLC12A1
Solute carrier family 12 member 1.
   
  
 0.749
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]
   
 0.685
SLC12A3
Solute carrier family 12 member 3.
   
  
 0.671
WNK1
WNK lysine deficient protein kinase 1.
    
 
 0.607
BSND
Barttin CLCNK type accessory beta subunit.
   
  
 0.597
KCNJ16
Potassium voltage-gated channel subfamily J member 16.
  
 
 
0.538
ABCC9
ATP binding cassette subfamily C member 9.
 
 
 0.520
ABCC8
ATP binding cassette subfamily C member 8.
 
 
 0.513
WNK3
WNK lysine deficient protein kinase 3.
    
 
 0.500
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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