STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RUNX2RUNX family transcription factor 2. (560 aa)    
Predicted Functional Partners:
MYSM1
Myb like, SWIRM and MPN domains 1.
    
 0.949
G3SWC6_LOXAF
Uncharacterized protein.
    
 0.881
SHH
Sonic hedgehog signaling molecule.
     
 0.830
ETS1
ETS proto-oncogene 1, transcription factor.
   
 0.727
ETS2
Protein C-ets-2; Transcription factor; Belongs to the ETS family.
   
 0.632
BGLAP
Osteocalcin; Binds strongly to apatite and calcium.
    
 0.630
MSX2
Msh homeobox 2.
    
 0.618
TAL1
TAL bHLH transcription factor 1, erythroid differentiation factor.
    
 0.615
CTNNB1
Catenin beta 1.
    
 0.605
ZFHX3
Zinc finger homeobox 3.
     
 0.604
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.