Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
MIOSMeiosis regulator for oocyte development. (875 aa)    
Predicted Functional Partners:
WDR24
WD repeat domain 24.
    
 0.998
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
    
 0.998
WDR59
WD repeat domain 59.
    
0.998
SESN2
Sestrin 2.
    
 0.998
NPRL2
NPR2 like, GATOR1 complex subunit.
    
 0.997
SEH1L
SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family.
    
 0.997
DEPDC5
DEP domain-containing protein.
    
 0.997
NPRL3
NPR3 like, GATOR1 complex subunit.
    
 0.997
KPTN
Kaptin, actin binding protein.
    
 0.980
RRAGC
Ras related GTP binding C.
    
 0.973
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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