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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEC14L3SEC14 like lipid binding 3. (400 aa)    
Predicted Functional Partners:
SLC1A6
Amino acid transporter.
   
 
 0.520
SLC1A7
Amino acid transporter.
   
 
 0.515
ASMT
Acetylserotonin O-methyltransferase.
   
  
 0.480
MTNR1B
Melatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.471
SLC1A1
Amino acid transporter.
   
 
 0.467
POLM
DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family.
      
 0.457
F12
Coagulation factor XII; Belongs to the peptidase S1 family.
   
 
 0.456
SLC6A18
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
    
 
 0.455
MAP3K19
Mitogen-activated protein kinase kinase kinase 19.
   
  
 0.427
AANAT
Aralkylamine N-acetyltransferase.
   
  
 0.418
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.