Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LGALS3Galectin. (250 aa)    
Predicted Functional Partners:
LGALS3BP
SRCR domain-containing protein.
    
 
 0.971
ALOX5AP
Arachidonate 5-lipoxygenase activating protein.
   
  
 0.899
LGALS1
Galectin.
   
 0.899
LAMP1
Lysosomal associated membrane protein 1.
    
 0.842
GPNMB
Glycoprotein nmb.
   
 
 0.730
EGFR
Receptor protein-tyrosine kinase.
    
 
 0.722
SLC12A2
Solute carrier family 12 member 2.
    
 
 0.689
ALCAM
Activated leukocyte cell adhesion molecule.
    
 
 0.677
CLEC7A
C-type lectin domain containing 7A.
   
 0.675
MERTK
MER proto-oncogene, tyrosine kinase.
   
 
 0.673
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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