Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1470 aa)    
Predicted Functional Partners:
NCAPG2
Non-SMC condensin II complex subunit G2.
   
 0.999
NCAPH2
Non-SMC condensin II complex subunit H2.
   
 0.999
SMC4
Structural maintenance of chromosomes protein.
   
 0.998
SMC2
Structural maintenance of chromosomes protein.
   
 0.997
NCAPH
Non-SMC condensin I complex subunit H.
   
 0.911
NCAPD2
Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
   
 
0.830
NCAPG
Non-SMC condensin I complex subunit G.
   
 
 0.770
PLK1
Serine/threonine-protein kinase PLK.
   
 0.762
RB1
RB transcriptional corepressor 1.
   
 0.743
MCPH1
BRCT domain-containing protein.
   
 0.730
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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