STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTGFRProstaglandin F receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)    
Predicted Functional Partners:
GNA13
G protein subunit alpha 13.
   
  0.876
GNA12
G protein subunit alpha 12.
   
  0.876
AVP
Neurophysin 2; Neurophysin 2 specifically binds vasopressin; Belongs to the vasopressin/oxytocin family.
    
 0.874
AGT
Angiotensinogen; Belongs to the serpin family.
    
 0.871
CXCL8
Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family.
     
  0.870
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
  0.870
F2R
Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.
     
 0.858
LOC100669226
Uncharacterized protein.
     
  0.855
GNAL
G protein subunit alpha L.
    
 0.806
G3UF61_LOXAF
Uncharacterized protein.
    
 0.806
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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