Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CD53Tetraspanin. (217 aa)    
Predicted Functional Partners:
LAPTM5
Lysosomal protein transmembrane 5.
   
  
 0.912
PTPRC
Protein tyrosine phosphatase receptor type C.
   
 0.788
CD48
Ig-like domain-containing protein.
   
 
 0.778
LCP1
Lymphocyte cytosolic protein 1.
   
    0.691
CD63
Tetraspanin.
   
 
 0.675
ITGB2
Integrin beta.
   
 0.639
LCP2
Lymphocyte cytosolic protein 2.
   
  
 0.636
TSPAN3
Tetraspanin.
     
 0.613
EVI2B
Ecotropic viral integration site 2B.
   
  
 0.552
TSPAN9
Tetraspanin.
     
  0.524
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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