STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)    
Predicted Functional Partners:
SKA2
Spindle and kinetochore associated complex subunit 2.
    
 0.996
SKA3
Spindle and kinetochore associated complex subunit 3.
   
 0.989
PLK1
Serine/threonine-protein kinase PLK.
   
 
 0.959
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.945
NDC80
NDC80 kinetochore complex component.
   
 0.936
NUF2
NUF2 component of NDC80 kinetochore complex.
   
 0.913
NUDC
Nuclear distribution C, dynein complex regulator.
     
  0.912
SGO1
Shugoshin 1.
   
 
 0.910
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 
 0.904
KIF18A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.864
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.