Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FARP1FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1046 aa)    
Predicted Functional Partners:
CDC42
Uncharacterized protein.
    
 0.789
MYO10
Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.658
RHOF
Ras homolog family member F, filopodia associated.
     
 0.587
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma.
     
 0.562
NRP1
Neuropilin; Belongs to the neuropilin family.
     
 0.538
ITSN2
Intersectin 2.
     
 0.537
G3U095_LOXAF
Uncharacterized protein.
     
 0.537
ALCAM
Activated leukocyte cell adhesion molecule.
     
 0.535
AFDN
Afadin, adherens junction formation factor.
      
 0.532
SDC1
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 
 0.532
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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