Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CISD1CDGSH iron sulfur domain 1. (108 aa)    
Predicted Functional Partners:
CISD3
CDGSH iron sulfur domain 3.
   
  
 0.858
CARS1
Cysteinyl-tRNA synthetase.
      
 0.699
G3SS82_LOXAF
Uncharacterized protein.
    
 
 0.686
TOMM70
Translocase of outer mitochondrial membrane 70.
      
 0.649
MIEN1
Migration and invasion enhancer 1.
   
  
 0.586
IREB2
Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family.
   
 
 0.561
ATP5PD
ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...]
   
 
 0.545
DDB1
Damage specific DNA binding protein 1.
    
 
 0.521
BCAP31
B cell receptor associated protein 31.
    
   0.506
UBQLN4
Ubiquilin 4.
      
 0.496
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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