Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CNTRLCentriolin. (2346 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.841
CCDC120
Coiled-coil domain containing 120.
    
 0.781
NIN
Uncharacterized protein.
   
 
 0.768
CEP128
Centrosomal protein 128.
   
 0.762
CCDC68
Coiled-coil domain containing 68.
     
 0.749
CEP250
Centrosomal protein 250.
   
  
 0.688
CEP170
Centrosomal protein 170.
    
 0.671
C1GALT1
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
     
 0.644
HOOK2
Hook microtubule tethering protein 2.
      
 0.630
CEP135
Uncharacterized protein.
   
 0.611
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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