STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAK4P21 (RAC1) activated kinase 4. (579 aa)    
Predicted Functional Partners:
CDC42
Uncharacterized protein.
   
 0.958
PAK6
Non-specific serine/threonine protein kinase.
   
 0.876
NCK2
Cytoplasmic protein.
    
 0.872
NCK1
Cytoplasmic protein.
    
 0.872
INKA1
Inka box actin regulator 1.
    
 
 0.840
MYLK4
Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily.
  
 
0.824
LIMK1
LIM domain kinase 1.
    
 0.824
LIMK2
LIM domain kinase 2.
    
 0.820
STK10
Uncharacterized protein.
 
 
    0.813
PAK2
Non-specific serine/threonine protein kinase.
    
  0.805
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.