Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DESI2Desumoylating isopeptidase 2. (194 aa)    
Predicted Functional Partners:
TIMM29
Translocase of inner mitochondrial membrane 29.
      
 0.672
METTL14
Methyltransferase like 14; Belongs to the MT-A70-like family.
   
 
 0.664
G3T461_LOXAF
Uncharacterized protein.
      
 0.574
METTL3
Methyltransferase like 3; Belongs to the MT-A70-like family.
   
 
 0.546
PSMD4
Proteasome 26S subunit, non-ATPase 4.
    
 
 0.524
PSMC4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
   
   0.501
PSMC3
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
   
   0.501
PSMD12
Proteasome 26S subunit, non-ATPase 12.
   
   0.500
PSMC5
Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.
   
   0.499
USPL1
Ubiquitin specific peptidase like 1.
      
 0.496
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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