STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ICA1Islet cell autoantigen 1. (485 aa)    
Predicted Functional Partners:
PICK1
Protein interacting with PRKCA 1.
   
 
 0.722
RAB2A
RAB2A, member RAS oncogene family.
    
 
 0.617
RHOBTB3
Rho related BTB domain containing 3.
    
 
 0.590
RALGAPA2
Rap-GAP domain-containing protein.
      
 0.575
KIF26B
Kinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.560
PTPRD
Protein tyrosine phosphatase receptor type D.
      
 0.556
ERC2
Uncharacterized protein.
      
 0.555
PTPRT
Uncharacterized protein.
      
 0.553
FAM117B
Family with sequence similarity 117 member B.
      
 0.496
CAMTA1
Calmodulin binding transcription activator 1.
      
 0.487
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.