STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C17orf75Chromosome 17 open reading frame 75. (394 aa)    
Predicted Functional Partners:
VPS25
Vacuolar protein sorting 25 homolog.
   
 0.954
SNF8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
    
 0.943
VPS36
Vacuolar protein sorting 36 homolog.
    
 0.921
CHMP2A
Charged multivesicular body protein 2A.
   
 0.892
VPS4B
Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.
    
 0.870
VPS4A
Uncharacterized protein; Belongs to the AAA ATPase family.
    
 0.870
FAM91A1
Family with sequence similarity 91 member A1.
    
 
 0.844
VPS28
Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.
   
 0.822
CHMP7
Charged multivesicular body protein 7.
    
 0.795
CHMP4C
Charged multivesicular body protein 4C.
    
 0.776
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.