Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPECarboxypeptidase E. (476 aa)    
Predicted Functional Partners:
CPB2
Carboxypeptidase B2.
  
 
 0.938
PCSK1
Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.
   
  
 0.703
PCSK1N
Proprotein convertase subtilisin/kexin type 1 inhibitor.
   
  
 0.656
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.642
PCSK2
Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family.
   
  
 0.604
CPB1
Carboxypeptidase B1.
  
 
 0.599
MYOM2
Myomesin 2.
      
 0.592
CPA6
Carboxypeptidase A6.
  
 
 0.575
PEX11B
Peroxisomal biogenesis factor 11 beta.
      
 0.573
SPCS2
Signal peptidase complex subunit 2.
      
 0.567
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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