PAX4 protein (Loxodonta africana) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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filled nodes:
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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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[Homology]

Score

PAX4

Paired box 4. (350 aa)

Predicted Functional Partners:

INS

0.822

SUZ12

0.738

SST

0.737

NEUROG3

0.725

FOXA1

0.714

FOXA2

0.679

POU1F1

0.653

NKX2-2

0.645

G3T461_LOXAF

0.619

MYB

0.619

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOXA1	FOXA2	ENSLAFP00000026280	ENSLAFP00000025082	Forkhead box A1.	Forkhead box A2.	0.428
FOXA1	NKX2-2	ENSLAFP00000026280	ENSLAFP00000001990	Forkhead box A1.	NK2 homeobox 2.	0.418
FOXA1	PAX4	ENSLAFP00000026280	ENSLAFP00000004435	Forkhead box A1.	Paired box 4.	0.714
FOXA2	FOXA1	ENSLAFP00000025082	ENSLAFP00000026280	Forkhead box A2.	Forkhead box A1.	0.428
FOXA2	INS	ENSLAFP00000025082	ENSLAFP00000015739	Forkhead box A2.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.675
FOXA2	NKX2-2	ENSLAFP00000025082	ENSLAFP00000001990	Forkhead box A2.	NK2 homeobox 2.	0.591
FOXA2	PAX4	ENSLAFP00000025082	ENSLAFP00000004435	Forkhead box A2.	Paired box 4.	0.679
G3T461_LOXAF	PAX4	ENSLAFP00000008112	ENSLAFP00000004435	Uncharacterized protein.	Paired box 4.	0.619
INS	FOXA2	ENSLAFP00000015739	ENSLAFP00000025082	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Forkhead box A2.	0.675
INS	NEUROG3	ENSLAFP00000015739	ENSLAFP00000027582	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neurogenin 3.	0.493
INS	NKX2-2	ENSLAFP00000015739	ENSLAFP00000001990	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NK2 homeobox 2.	0.604
INS	PAX4	ENSLAFP00000015739	ENSLAFP00000004435	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Paired box 4.	0.822
INS	SST	ENSLAFP00000015739	ENSLAFP00000010283	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Somatostatin.	0.782
MYB	PAX4	ENSLAFP00000015379	ENSLAFP00000004435	MYB proto-oncogene, transcription factor.	Paired box 4.	0.619
NEUROG3	INS	ENSLAFP00000027582	ENSLAFP00000015739	Neurogenin 3.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.493
NEUROG3	NKX2-2	ENSLAFP00000027582	ENSLAFP00000001990	Neurogenin 3.	NK2 homeobox 2.	0.597
NEUROG3	PAX4	ENSLAFP00000027582	ENSLAFP00000004435	Neurogenin 3.	Paired box 4.	0.725
NKX2-2	FOXA1	ENSLAFP00000001990	ENSLAFP00000026280	NK2 homeobox 2.	Forkhead box A1.	0.418
NKX2-2	FOXA2	ENSLAFP00000001990	ENSLAFP00000025082	NK2 homeobox 2.	Forkhead box A2.	0.591
NKX2-2	INS	ENSLAFP00000001990	ENSLAFP00000015739	NK2 homeobox 2.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.604

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