Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
FBXL4F-box and leucine rich repeat protein 4. (622 aa)    
Predicted Functional Partners:
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.881
UHRF2
Ubiquitin like with PHD and ring finger domains 2.
      
 0.822
BNIP3L
BCL2 interacting protein 3 like.
    
 
 0.820
BNIP3
BCL2 interacting protein 3.
    
 
 0.814
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.797
G3U9C6_LOXAF
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.797
G3ULX5_LOXAF
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.797
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
      
 0.706
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.705
DENND4A
DENN domain containing 4A.
      
 0.684
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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