node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C17orf64 | KDM1A | ENSLAFP00000025429 | ENSLAFP00000006696 | Chromosome 17 open reading frame 64. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.403 |
C17orf64 | RREB1 | ENSLAFP00000025429 | ENSLAFP00000004443 | Chromosome 17 open reading frame 64. | Ras responsive element binding protein 1. | 0.401 |
CHD1 | KDM1A | ENSLAFP00000017447 | ENSLAFP00000006696 | Chromodomain helicase DNA binding protein 1. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.454 |
CHD1 | RREB1 | ENSLAFP00000017447 | ENSLAFP00000004443 | Chromodomain helicase DNA binding protein 1. | Ras responsive element binding protein 1. | 0.401 |
IRF1 | RREB1 | ENSLAFP00000006310 | ENSLAFP00000004443 | Interferon regulatory factor. | Ras responsive element binding protein 1. | 0.488 |
KDM1A | C17orf64 | ENSLAFP00000006696 | ENSLAFP00000025429 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Chromosome 17 open reading frame 64. | 0.403 |
KDM1A | CHD1 | ENSLAFP00000006696 | ENSLAFP00000017447 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Chromodomain helicase DNA binding protein 1. | 0.454 |
KDM1A | RREB1 | ENSLAFP00000006696 | ENSLAFP00000004443 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Ras responsive element binding protein 1. | 0.512 |
NFE2L2 | RREB1 | ENSLAFP00000013652 | ENSLAFP00000004443 | Nuclear factor, erythroid 2 like 2. | Ras responsive element binding protein 1. | 0.521 |
PHF20 | RREB1 | ENSLAFP00000008668 | ENSLAFP00000004443 | PHD finger protein 20. | Ras responsive element binding protein 1. | 0.468 |
RREB1 | C17orf64 | ENSLAFP00000004443 | ENSLAFP00000025429 | Ras responsive element binding protein 1. | Chromosome 17 open reading frame 64. | 0.401 |
RREB1 | CHD1 | ENSLAFP00000004443 | ENSLAFP00000017447 | Ras responsive element binding protein 1. | Chromodomain helicase DNA binding protein 1. | 0.401 |
RREB1 | IRF1 | ENSLAFP00000004443 | ENSLAFP00000006310 | Ras responsive element binding protein 1. | Interferon regulatory factor. | 0.488 |
RREB1 | KDM1A | ENSLAFP00000004443 | ENSLAFP00000006696 | Ras responsive element binding protein 1. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.512 |
RREB1 | NFE2L2 | ENSLAFP00000004443 | ENSLAFP00000013652 | Ras responsive element binding protein 1. | Nuclear factor, erythroid 2 like 2. | 0.521 |
RREB1 | PHF20 | ENSLAFP00000004443 | ENSLAFP00000008668 | Ras responsive element binding protein 1. | PHD finger protein 20. | 0.468 |
RREB1 | STK32A | ENSLAFP00000004443 | ENSLAFP00000010883 | Ras responsive element binding protein 1. | Serine/threonine kinase 32A. | 0.435 |
STK32A | RREB1 | ENSLAFP00000010883 | ENSLAFP00000004443 | Serine/threonine kinase 32A. | Ras responsive element binding protein 1. | 0.435 |